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I focus on joy, happiness, health, creativity, & productivity, including my 5 decades of holistic health experience with rigor & a pragmatic approach. You can subscribe to my content here or my health/wellness newsletter: .

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4 Well-Research Benefits of Trimethylglycine (TMG) as a Methyl Donor Addressing Homocysteine

12 min readFeb 5, 2024

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Cardiometabolic diseases claim millions of lives worldwide, with elevated homocysteine levels and chronic inflammation being significant contributors. Numerous studies link the trimethylglycine (TMG) molecule to heart health, suggesting that maintaining healthy homocysteine levels supports optimal cardiovascular function.

Interestingly, like CoQ10, trimethylglycine has been recognized as a heart-health-promoting amino acid since the 1950s, but it is still not well-known compared to hyped supplements on the market.

Recently, I wrote a story titled MTHFR Polymorphisms or Mutations: Getting Checked to Prevent Cardiovascular Issues. Discerning readers, seeing one of the methylation donors as TMG, asked me to introduce this vital molecule and how they can benefit from it safely through food or supplementation.

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Published in EUPHORIA

I focus on joy, happiness, health, creativity, & productivity, including my 5 decades of holistic health experience with rigor & a pragmatic approach. You can subscribe to my content here or my health/wellness newsletter: .

Dr Mehmet Yildiz
Dr Mehmet Yildiz

Written by Dr Mehmet Yildiz

Scientist, Technologist, Inventor, focusing on HEALTH and JOY. Founder of ILLUMINATION, curating key messages for society. Connection: